RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-152
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
NA
Pathway
HEDGEHOG SIGNALING PATHWAY
PubMed ID
Title
Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation
Year
2015
Function
"Mir-378a expression is associated with its methylation status in tgf-b1-treated cells, and epigenetically-regulated mir-378a inhibits tgf-beta1-induced hsc activation, at least in part, via tgf-b2."
RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-152
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
immunofluorescence; immunohistochemistry; etc.
Target
PTCH1
Pathway
NA
PubMed ID
Title
Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation
Year
2015
Function
Salvianolic acid b-induced microrna-152 inhibits liver fibrosis by attenuating dnmt1-mediated patched1 methylation.